Newborn Nursery at LPCH

Guidelines for Vitamin K Prophylaxis

The success of vitamin K prophylaxis has been so dramatic that many practitioners have never seen an infant afflicted with "Hemorrhagic Disease of the Newborn", now known as "Vitamin K Deficient Bleeding".  It is a popular trend in some areas to refuse prophylaxis in an effort to keep things "natural" for the infant, however, it is important to keep in mind that the infants most at risk for the classic form of the disease are healthy babies who are exclusively breastfed.

Background

Problem

Definitions/Presentation/Diagnosis/Treatment

Risk Factors

Prophylaxis

Adressing Parental Concerns

References

 

Background

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Problem

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Definitions/Presentation/Diagnosis/Treatment

DEFINITIONS

PRESENTATION

Items in italics are most common form of initial presentation.

DIAGNOSIS                                                                                        

TREATMENT

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Risk Factors

EARLY DISEASE

CLASSIC DISEASE

LATE DISEASE

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Prophylaxis

 

   If parents refuse IM vitamin K:

(See notes below about oral regimens)

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Addressing Parental Concerns

Does vitamin K cause cancer?

Does vitamin K cause jaundice?

What other side effects have been reported?

JAbyMD, reviewed 5/06

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References

American Academy of Pediatrics, Committee on Fetus and Newborn.  Controversies Concerning Vitamin K and the Newborn.  Pediatrics 2003 July; 112(1):191-2.

Ross, JA, Davies SM. Vitamin K prophylaxis and childhood cancer. Med Pediatr Oncol. 2000 Jun;34(6):434-7.

Cornelissen, M., et al.  Prevention of vitamin K deficiency bleeding: efficacy of different multiple oral dose schedules of vitamin K.  Eur J Pediatr.  1997 Feb; 156(2):126-30.

Greer, FR, et al. Improving the vitamin K status of breastfeeding infants with maternal vitamin K supplements. Pediatr. 1997 Jan;99(1).

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